FROM BIOINFORMATICS TO CLINICAL APPLICATIONS: A NOVEL PROGNOSTIC MODEL OF CUPROPTOSIS-RELATED GENES BASED ON SINGLE-CELL RNA SEQUENCING DATA IN HEPATOCELLULAR CARCINOMA

Abstract Objective and methods To ascertain the connection between cuproptosis-related genes (CRGs) and the prognosis of hepatocellular carcinoma (HCC) via single-cell RNA sequencing (scRNA-seq) and RNA sequencing (RNA-seq) data, relevant data were downloaded from the GEO and TCGA databases.The differentially expressed CRGs (DE-CRGs) were filtered

One challenge to understanding mechanisms of behavior opi all about the bows change (MOBC) completely among individuals with alcohol use disorder is that processes of change are theorized to be complex, dynamic (time varying), and at times non-linear, and they interact with each other to influence alcohol consumption.We used dynamical systems model

Foreign Direct Investment (FDI) is one of the forms of international investment that has significantly contributed to the prosperity of the host country.However, with the growth of the economy, investment disputes have been on the rise, involving both investors and the host government.While Undang-Undang Nomor 25 Tahun 2007 provides sufficient lega

Grafting technology can improve the yield and quality of crops.In this study, we investigated the effects of grafting on watermelon using transcriptomic and metabolomic analysis.A total of 216 differentially accumulated metabolites (DAMs) were identified between pumpkin-grafted watermelon and self-grafted watermelon.KO (Kyoto Encyclopedia of Genes